Oncology IQ
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Three hours after receiving a packed red blood cell transfusion, a patient becomes short of breath. Vital signs reveal oxygen saturation, 88% on room air, blood pressure, 92/54 mm Hg and temperature, 101.5°F(38.6°C). What is the patient most likely experiencing?
a. Transfusion-associated circulatory overload
b. Acute hemolytic reaction
c. Febrile nonhemolytic reaction
d. Transfusion-related acute lung injury
Answer
d. Transfusion-related acute lung injury
Rationale:
Transfusion-related acute lung injury symptoms can develop up to six hours after a transfusion.
Reference:
Forman, S.J., Negrin, R.S., Antin, J.H., & Appelbaum, F.R. (Eds.). (2016). Thomas’ hematopoietic cell transplantation (5th ed.). John Wiley & Sons, pp. 970-971.